Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on identifying, developing, and commercializing treatments involving bacterial infections, including multi-drug resistant bacterial infections, and rare diseases. Its pipeline product candidates include Tebipenem HBr, SPR720, and SPR206. The company is headquartered in Cambridge, Massachusetts and currently employs 32 full-time employees. The company went IPO on 2017-11-02. The firm is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr, is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs), including acute pyelonephritis (AP), to help patients potentially reduce duration of in-patient therapy.
Financials in millions USD. Fiscal year is February - January.
Breakdown
TTM
03/31/2026
12/31/2025
09/30/2025
06/30/2025
03/31/2025
Revenue
61
0
41
5
14
5
Revenue Growth (YoY)
39%
-100%
173%
-62%
40%
-44%
Cost of Revenue
--
--
--
--
--
--
Gross Profit
--
--
--
--
--
--
Selling, General & Admin
19
4
4
4
5
6
Research & Development
27
2
5
8
10
13
Operating Expenses
47
7
9
12
16
20
Other Non Operating Income (Expenses)
0
0
0
0
0
0
Pretax Income
15
-7
31
-7
-1
-13
Income Tax Expense
--
--
0
0
--
--
Net Income
15
-7
31
-7
-1
-13
Net Income Growth
-122%
-46%
-254.99%
-59%
-94%
8%
Shares Outstanding (Diluted)
57.28
57.28
68.55
56.28
56.02
55.37
Shares Change (YoY)
3%
3%
26%
4%
4%
3%
EPS (Diluted)
0.26
-0.12
0.45
-0.13
-0.03
-0.25
EPS Growth
-121%
-50%
-220%
-59%
-91%
6%
Free Cash Flow
7
15
-8
17
-17
-4
Free Cash Flow Per Share
--
--
--
--
--
--
Gross Margin
--
--
--
--
--
--
Operating Margin
22.95%
0%
75.6%
-140%
-14.28%
-280%
Profit Margin
24.59%
0%
75.6%
-140%
-7.14%
-260%
Free Cash Flow Margin
11.47%
0%
-19.51%
340%
-121.42%
-80%
EBITDA
--
--
31
-7
-2
--
EBITDA Margin
--
--
75.6%
-140%
-14.28%
--
D&A For EBITDA
--
--
0
0
0
--
EBIT
14
-7
31
-7
-2
-14
EBIT Margin
22.95%
0%
75.6%
-140%
-14.28%
-280%
Effective Tax Rate
--
--
0%
0%
--
--
Follow-Up Questions
What are Spero Therapeutics Inc's key financial statements?
According to the latest financial statement (Form-10K), Spero Therapeutics Inc has a total asset of $0, Net loss of $0
What are the key financial ratios for SPRO?
Spero Therapeutics Inc's Current ratio is 0, has a Net margin is 0, sales per share of $0.
How is Spero Therapeutics Inc's revenue broken down by segment or geography?
Spero Therapeutics Inc largest revenue segment is Novel Treatments for Multi-drug Resistant Bacterial Infections, at a revenue of 103,781,000 in the most earnings release.For geography, United States is the primary market for Spero Therapeutics Inc, at a revenue of 103,781,000.
Is Spero Therapeutics Inc profitable?
no, according to the latest financial statements, Spero Therapeutics Inc has a net loss of $0
Does Spero Therapeutics Inc have any liabilities?
no, Spero Therapeutics Inc has liability of 0
How many outstanding shares for Spero Therapeutics Inc?
Spero Therapeutics Inc has a total outstanding shares of 0