Leap Therapeutics, Inc. is a clinical stage biopharmaceutical company, which engages in developing novel therapies designed to treat patients with cancer. The company is headquartered in Cambridge, Massachusetts and currently employs 52 full-time employees. The company went IPO on 2017-01-24. The firm is engaged in developing novel biomarker-targeted antibody therapies designed to treat patients with cancer by inhibiting fundamental tumor-promoting pathways. The Company’s lead clinical stage drug candidate is sirexatamab (DKN-01), a monoclonal antibody that inhibits Dickkopf-related protein 1 (DKK1). DKK1 is also a modulator of CKAP4/PI3K/AKT signaling. The firm is developing DKN-01 in a clinical trial in patients with colorectal cancer and has also conducted clinical trials in patients with gastric/gastroesophageal junction cancer and endometrial cancer patients. The firm also has a preclinical program to develop a proprietary monoclonal antibody known as FL-501. FL-501 is a monoclonal antibody in preclinical development that targets growth and differentiation factor 15 (GDF15), which is a cytokine that is produced at elevated levels in response to various stresses.
Based on 6 analysts giving stock ratings to CYPH, updated on Dec 01, 2025
Sell
Strong buy
0
Buy
0
Hold
3
Sell
1
Strong sell
2
Based on comprehensive analyst evaluations, we have synthesized critical insights from expert assessments to outline a cautious outlook for CYPH. Analysts note deteriorating fundamentals and challenging market sentiment, indicating potential downside risks in the near term. Following this expert analysis, we adopt a bearish stance on this stock. Our conclusion: CYPH is a Sell candidate.
CYPH stock price ended at $0.69 on Friday, after rising 13.11%
On the latest trading day Feb 06, 2026, the stock price of CYPH rose by 13.11%, climbing from $0.64 to $0.69. Throughout the session, the stock experienced a volatility of 20.31%, with prices fluctuating between a daily low of $0.64 and a high of $0.77. Alongside this price increase, trading volume also rose by 1.7M shares, reflecting strong market interest that may signal continued bullish momentum in the near term. In total, 3.1M shares were traded, amounting to a market value of approximately $39.0M.
CYPH Technical Signals
Technical Signals Summary
Buy Signals 1
Neutral Signals 2
Sell Signals 4
Strong Sell
Sell
Neutral
Buy
Strong Buy
CYPH currently exhibits 1 buy signals and 4 sell signals. The stock has been in an uptrend since 12:00 AM, with a total price change of 13.11% during this period. Overall, the technical indicators point to a Sell outlook for the mid-term.
Bullish/Bearish Signals for CYPH
Our algorithms analyze key indicators like moving averages, RSI, MACD, and trading volume to generate bullish and bearish signals for CYPH. These insights help you make informed investment decisions.
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